Super-potent opioids could be safer-than-expected alternatives to conventional painkillers

www.nature.com

Super-potent opioids could be safer-than-expected alternatives to conventional painkillers

www.nature.com

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Nature@ibbit.atEnglish · 26 days ago

Nature, Published online: 01 April 2026; doi:10.1038/d41586-026-00806-3

Modified nitazenes, opioids 1,000 times stronger than morphine, show remarkably few adverse effects in rodents, renewing the potential of these drugs for pain relief.

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Nature is a weekly international journal publishing the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature also provides rapid, authoritative, insightful and arresting news and interpretation of topical and coming trends affecting science, scientists and the wider public.

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