Zero, I scroll with my index finger.

TLDR, we’re fucked. We have been exposed to tons of harmful chemicals and they’re inside us, from lead to pesticides and microplastics, and maybe we’ll understand how they fuck us up.

When the Venn diagram is a circle. :(

Ain’t no step about it.

Not monkey but rocky mountain oysters.

My vehicle gets washed when it rains, and I live in the US southwest.

In my opinion, no. It is picked and consumed when the buds are still tight, if the head starts to loosen or the buds begin to open it has a more bitter taste to it.

5-10 steps ahead of them after they lapped them twice and going for a third. A lot of people just don’t seem to understand how much time and passion scientist put into their research.

From the research paper (behind the paywall) it appears they only tested cancer cells, shown below, and on mouse models. It’s been awhile since I’ve studied this, so I don’t know if the proteins involved are specific to cancer cells or not. If not I’d assume it would kill all cells. With the mouse models I assume they injected directly into the tumor for targeted treatment, but I didn’t dive into it that deep.

Paper link: https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202500412R?saml_referrer

2.2 Cell Culture

Human monocyte-like THP-1 leukemia cells (THP-1, THP-1Asc-KO, THP-1Gsdmd-KO, THP-1-Null, THP-1-defCasp1, and THP-1-defNLRP3) [4, 21] were provided by Professor Li Sun’s lab (Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China), and human liver cancer Huh7.5 cells were maintained in our lab. THP-1 cells and Huh7.5 cells were cultured in RPMI 1640 medium with 10% FBS, 100 U/mL penicillin, and 100 μg/mL streptomycin at 37°C in a 5% CO2 humidified incubator. All experiments were carried out with the same batch of cell lines between passages 2 and 8.

2.15 Xenograft Tumor Mouse Model

BALB/C nu-nu male mice, 4 weeks old, were obtained from Beijing Vital River Laboratory Animal Technology Co. Ltd. (Beijing, China). A total of 3 × 106 Huh7.5 cells were subcutaneously injected into the right fore flank of each nude mouse. The daily drug treatment began when the tumor size reached ~100 mm3 and continued for a further 2 weeks as follows: EPS3.9 (30 and 60 mg kg−1 d−1, intraperitoneal injection) dissolved in assisted solvent (PBS); Control groups were given the same volume of PBS. Body weight and tumor volumes were measured every day with a balance or with a vernier caliper. The tumor volume was calculated with the formula: 1/2 × [length × (width)2]. After treatment for 2 weeks, mice were sacrificed by decapitation and tumor tissues were collected for further analysis.

Is this how we curb our red meat issue and help the climate?

Don’t have open flames when opening that bad boy.

A mutt on a blunt

Actually an American, a lost treasure, Anthony Bourdain. Loved his shows.

Noice, glad I wasn’t the only one who recognized the show…feel old.

blah blah blah…Epstein files

About to get Epsteined à la Litvinenko style.

I pity the fool who don’t know about Mr. T’s chains.

Drain the swamp!

How does it go?

Rules for thee, not for me.

A good book on this is: Free Culture: The Nature and Future of Creativity by Lawrence Lessig